My doctoral research centred on the prognosis and management of cirrhotic portal hypertension, University of Liverpool.
Systematic review to Cochrane standards, including protocol development and registration. Meta-analysis, including aggregate-data methods with time-to-event outcomes. Trial sequential analysis. Critical appraisal and registration of hepatobiliary trials at editorial level.
Randomised controlled trial design, including double-blind sham-controlled design. Multicentre trial delivery as site principal investigator. Prospective diagnostic accuracy studies with parallel health economic analysis.
Long-term prospective cohort studies. Case-control design. Cross-sectional studies. Multicentre audit methodology.
Survival analysis. Univariate and multivariate prognostic modelling. Development and validation of predictive models. Database design. Direct collaboration with medical statisticians, including publication in a statistics journal.
Immunohistochemical expression analysis. Molecular genetic analysis including allelotyping. Physiological measurement — hepatic venous pressure and portal blood flow.